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The Hepatitis B Research Network brings together clinical centers with expertise in caring for patients with chronic hepatitis B virus (HBV) infection. An estimated 2 billion people worldwide have been infected with HBV and about 400 million persons are living with chronic HBV infection. Of those with childhood-acquired chronic HBV infection, it is estimated that 25% will later die from the liver-related complications of cancer and cirrhosis if left untreated. The prevalence of HBV infection is uneven throughout the world, with significant burdens in Asia and the Pacific Islands, sub-Saharan Africa, the Amazon Basin, and Eastern Europe. National surveys indicate that 0.3% to 0.5% of U.S. residents have chronic HBV infection, and 47% to 70% of these persons were born outside the United States. The goal of the Network is to conduct research on chronic hepatitis B, in order to better understand the physiological effects of the disease and develop effective treatment strategies with the currently available therapies.

This web site is designed to inform the public of the research activities conducted by the Hepatitis B Research Network. It is also a portal to support communications for our researchers and participants in our studies.





The Hepatitis B Research Network is currently seeking patients for a multi-center prospective study of the natural history of chronic hepatitis B. Within the next few months treatment trials for various patients with chronic hepatitis B will also begin enrolling patients. Details of the entry criteria for these studies can be obtained from the clinical centers outlined on the map below.

Adult Enrolling Cities Ann Arbor, MI Michigan Hawaii Consortium University of Michigan Health System City: Ann Arbor, MI Contact: Diane White Phone: 734-763-6647 Fax: 734-615-3844 Email: dfwhite@umich.edu Contact: Sravanthi Kaza Phone: 734-615-3853 Email: sravath@umich.edu Link: www.umclinicalstudies.org University of Hawaii/Hawaii Medical Center East City: Honolulu, HI Contact: Diane Cain Phone: 808-547-6543 Fax: 808-533-1324 Email: DCain@hawaiimedcen.com Boston, MA Harvard Beth Israel Deaconess Medical Center (BIDMC) City: Boston, MA Contact: Johann Han Phone: 617-632-9716 Fax: 617-632-1125 Email: jahan@bidmc.harvard.edu Contact: Jianghe Niu Phone: 617-632-1119 Fax: 617-632-1125 Email: jniu@bidmc.harvard.edu Massachusetts General Hospital City: Boston, MA Contact: Jenna Gustafson Phone: 617-724-3836 Fax: 617-724-1091 Email: jlgustafson@partners.org Bethesda, MD NIH Clinical Center City: Bethesda, MD Contact: Elenita Rivera Telephone: 301-435-6125 Fax: 301-451-9160 Email: erivera@cc.nih.gov Contact: Marc Ghany Phone: 301-402-5115 Fax: 301-402-0491 Email: marcg@intra.niddk.nih.gov Chapel Hill, NC Chapel Hill, NC University of North Carolina at Chapel Hill City: Chapel Hill, NC Contact: Tiffany Pritchett Phone: 919-966-0289 Fax: 919-843-2508 Email: tpritch@med.unc.edu Duke University Medical Center City: Durham, NC Contact: Catee Mullen Phone: 919-681-9479 Fax: 919-668-6110 Email: catee.mullen@duke.edu Dallas, TX HBV CRN North Texas University of Texas Southwestern City: Dallas, TX Contact: Jody Balko Phone: 214-645-6113 Fax: 214-645-6114 Email: jody.balko@utsouthwestern.edu Link: http://www.utsouthwestern.edu/patientcare/medicalservices/digestive/liver.html Baylor University Medical Center City: Dallas, TX Contact: Brigid Hayward Phone: 214-820-6242 Fax: 214-820-7142 Email: Brigid.hayward@baylorhealth.edu Children’s Medical Center Dallas City: Dallas, TX Contact: Margaret L. Cowie Phone: 214-456-1865 Fax: 214-456-7251 Email: margaret.cowie@childrens.com Contact: Norberto Rodriguez-Baez Phone: 214-456-8000 Email: Norberto.Rodriguez-Baez@childrens.com Durham, NC Chapel Hill, NC University of North Carolina at Chapel Hill City: Chapel Hill, NC Contact: Tiffany Pritchett Phone: 919-966-0289 Fax: 919-843-2508 Email: tpritch@med.unc.edu Duke University Medical Center City: Durham, NC Contact: Catee Mullen Phone: 919-681-9479 Fax: 919-668-6110 Email: catee.mullen@duke.edu Honolulu, HI Michigan Hawaii Consortium Queen's Medical Center - Liver Center City: Honolulu, HI Contact: Leslie Huddleston Phone: 808-691-7609 Fax: 808-691-1169 Email: lhuddleston@queens.org University of Michigan Health System City: Ann Arbor, MI Contact: Diane White Phone: 734-763-6647 Fax: 734-615-3844 Email: dfwhite@umich.edu Contact: Sravanthi Kaza Phone: 734-615-3853 Email: sravath@umich.edu Link: www.umclinicalstudies.org Los Angeles, CA Los Angeles Hepatitis B Consortium - UCLA University of California, Los Angeles City: Los Angeles, CA Contact: Val Peacock Phone: 310-794-6067 Fax: 310-794-3294 Email: vpeacock@mednet.ucla.edu Link: http://asianliverprogram.ucla.edu Cedars Sinai Medical Center City: Los Angeles, CA Contact: Tricia Hoang Phone: 310-423-5786 Fax: 310-423-1380 Email: tricia.hoang@cshs.org Link: www.csmc.edu Minneapolis, MN Minnesota Alliance for Research in Chronic Hepatitis B (MARCH-B) - Mayo Clinic Mayo Clinic City: Rochester, MN Contact: Linda Stadheim Phone: 507-284-0141 Fax: 507-266-0593 Email: Stadheim.linda@mayo.edu Contact: Janice Zimmerman Phone: 507-266-1287 Email: Zimmerman.janice@mayo.edu Link: www.MayoClinic.org University of Minnesota City: Minneapolis MN Contact: Teri Carlson Phone: 612-625-0673 Email: carls273@umn.edu University of Minnesota Amplatz Children's Hospital City: Minneapolis/St Paul, MN Contact: Sarah Jane Schwarzenberg, MD Phone: 612-624-1133 Fax: 612-626-0639 Email: schwa005@umn.edu Richmond, VA Virginia Commonwealth University Medical Center City: Richmond, VA Contact: Richard Sterling Phone: 804-828-4060 Fax: 804-828-4945 Email: rksterli@vcu.edu Rochester, MN Minnesota Alliance for Research in Chronic Hepatitis B (MARCH-B) - Mayo Clinic Mayo Clinic City: Rochester, MN Contact: Linda Stadheim Phone: 507-284-0141 Fax: 507-266-0593 Email: Stadheim.linda@mayo.edu Contact: Janice Zimmerman Phone: 507-266-1287 Email: Zimmerman.janice@mayo.edu Link: www.MayoClinic.org University of Minnesota City: Minneapolis MN Contact: Teri Carlson Phone: 612-625-0673 Email: carls273@umn.edu University of Minnesota Amplatz Children's Hospital City: Minneapolis/St Paul, MN Contact: Sarah Jane Schwarzenberg, MD Phone: 612-624-1133 Fax: 612-626-0639 Email: schwa005@umn.edu St. Louis, MO St. Louis Midwest Hep B Consortium Saint Louis University City: St. Louis, MO Contact: Debra King Phone: 314-977-9320 Fax: 314-977-1210 Email: kingdl@slu.edu Link: http://livercenter.slu.edu Saint Louis University (Pediatric site) City: St. Louis, MO Contact: Rosemary Nagy Phone: 314-268-2700 x 6144 Fax: 314-268-2775 Email: rnagy@slu.edu Contact: Jeffrey Teckman Phone: 314-577-5647 Fax: 314-268-2775 Email: teckmanj@slu.edu Washington University City: St. Louis, MO Contact: Mauricio Lisker-Melman Phone: 314-454-8141 Email: mlisker@dom.wustl.edu Link: http://gastro.wustl.edu Contact: Darlene Hoener Phone: 314-747-0647 Fax: 314-286-1538 Email: hoenerda@wusm.wustl.edu Contact: Christine DeBold Phone: 314-362-8655 Email: cdebold@dom.wustl.edu San Francisco, CA San Francisco Hepatitis B Research Group University of California San Francisco City: San Francisco, CA Contact: Annie Sharabidze Phone: 415-502-8612 Email: Ann.Sharabidze2@ucsf.edu University of California San Francisco (Pediatric site) Contact: Shannon Fleck Phone: 415-476-5892 Fax: 415-476-1343 Email: flecks@peds.ucsf.edu California Pacific Medical Center City: San Francisco, CA Contact: Natalie Bzowej Phone: 415-600-1028 Fax: 415-600-1200 Email: bzowejn@sutterhealth.org Seattle, WA PNW/Alaska Clinical Center Harborview Medical Center City: Seattle, WA Contact: Terri Mathisen Phone: 206-744-7053 Fax: 206-744-8698 Email: tmatis@uw.edu Contact: Erica Coppel Phone: 206-744-3402 Email: etc2@uw.edu Virginia Mason Medical Center City: Seattle, WA Contact: Jody Mooney Phone: 206-341-1452 or 206-341-1021 Fax: 206-341-0371 Email: Jody.Mooney@vmmc.org Seattle Children's Hospital City: Seattle, WA Contact: Karen Murray Phone: 206-987-4592 Fax: 206-987-2721 Email: Karen.murray@seattlechildrens.org Toronto, ON University of Toronto Toronto Western Hospital Liver Centre City: Toronto, ON Contact: Colina Yim Phone: 416-603-5976 Fax: 416-603-7175 Email: colina.yim@uhn.on.ca Hospital for Sick Children City: Toronto, ON Contact: Simon Ling Phone: 416-813-6176 Fax: 416-813-6531 Email: simon.ling@sickkids.ca

Pediatric Enrolling Cities Baltimore, MD Johns Hopkins School of Medicine City: Baltimore, MD Contact: Kathy Schwarz, MD Phone: 410-955-0781 Email: kschwarz@jhmi.edu City: Baltimore, MD Contact: Ying Yuan Phone: 410-955-9161 Fax: 410-614-1820 Email: yyuan19@jhmi.edu Dallas, TX HBV CRN North Texas University of Texas Southwestern City: Dallas, TX Contact: Jody Balko Phone: 214-645-6113 Fax: 214-645-6114 Email: jody.balko@utsouthwestern.edu Link: http://www.utsouthwestern.edu/patientcare/medicalservices/digestive/liver.html Baylor University Medical Center City: Dallas, TX Contact: Brigid Hayward Phone: 214-820-6242 Fax: 214-820-7142 Email: Brigid.hayward@baylorhealth.edu Children’s Medical Center Dallas City: Dallas, TX Contact: Margaret L. Cowie Phone: 214-456-1865 Fax: 214-456-7251 Email: margaret.cowie@childrens.com Contact: Norberto Rodriguez-Baez Phone: 214-456-8000 Email: Norberto.Rodriguez-Baez@childrens.com Minneapolis, MN Minnesota Alliance for Research in Chronic Hepatitis B (MARCH-B) - Mayo Clinic Mayo Clinic City: Rochester, MN Contact: Linda Stadheim Phone: 507-284-0141 Fax: 507-266-0593 Email: Stadheim.linda@mayo.edu Contact: Janice Zimmerman Phone: 507-266-1287 Email: Zimmerman.janice@mayo.edu Link: www.MayoClinic.org University of Minnesota City: Minneapolis MN Contact: Teri Carlson Phone: 612-625-0673 Email: carls273@umn.edu University of Minnesota Amplatz Children's Hospital City: Minneapolis/St Paul, MN Contact: Sarah Jane Schwarzenberg, MD Phone: 612-624-1133 Fax: 612-626-0639 Email: schwa005@umn.edu St. Louis, MO St. Louis Midwest Hep B Consortium Saint Louis University City: St. Louis, MO Contact: Debra King Phone: 314-977-9320 Fax: 314-977-1210 Email: kingdl@slu.edu Link: http://livercenter.slu.edu Saint Louis University (Pediatric site) City: St. Louis, MO Contact: Rosemary Nagy Phone: 314-268-2700 x 6144 Fax: 314-268-2775 Email: rnagy@slu.edu Contact: Jeffrey Teckman Phone: 314-577-5647 Fax: 314-268-2775 Email: teckmanj@slu.edu Washington University City: St. Louis, MO Contact: Mauricio Lisker-Melman Phone: 314-454-8141 Email: mlisker@dom.wustl.edu Link: http://gastro.wustl.edu Contact: Darlene Hoener Phone: 314-747-0647 Fax: 314-286-1538 Email: hoenerda@wusm.wustl.edu Contact: Christine DeBold Phone: 314-362-8655 Email: cdebold@dom.wustl.edu San Francisco, CA San Francisco Hepatitis B Research Group University of California San Francisco City: San Francisco, CA Contact: Annie Sharabidze Phone: 415-502-8612 Email: Ann.Sharabidze2@ucsf.edu University of California San Francisco (Pediatric site) Contact: Shannon Fleck Phone: 415-476-5892 Fax: 415-476-1343 Email: flecks@peds.ucsf.edu California Pacific Medical Center City: San Francisco, CA Contact: Natalie Bzowej Phone: 415-600-1028 Fax: 415-600-1200 Email: bzowejn@sutterhealth.org Seattle, WA PNW/Alaska Clinical Center Harborview Medical Center City: Seattle, WA Contact: Terri Mathisen Phone: 206-744-7053 Fax: 206-744-8698 Email: tmatis@uw.edu Contact: Erica Coppel Phone: 206-744-3402 Email: etc2@uw.edu Virginia Mason Medical Center City: Seattle, WA Contact: Jody Mooney Phone: 206-341-1452 or 206-341-1021 Fax: 206-341-0371 Email: Jody.Mooney@vmmc.org Seattle Children's Hospital City: Seattle, WA Contact: Karen Murray Phone: 206-987-4592 Fax: 206-987-2721 Email: Karen.murray@seattlechildrens.org Toronto, ON University of Toronto Toronto Western Hospital Liver Centre City: Toronto, ON Contact: Colina Yim Phone: 416-603-5976 Fax: 416-603-7175 Email: colina.yim@uhn.on.ca Hospital for Sick Children City: Toronto, ON Contact: Simon Ling Phone: 416-813-6176 Fax: 416-813-6531 Email: simon.ling@sickkids.ca